Ground truth for agentic biology.

Agents design candidates. Models predict interactions. There is still no way to measure, at that same scale, which ones function in the real world. Lagomics runs one pooled, sequencing-based experiment that measures interactions across your entire candidate library at once: protein-protein, peptide-target, or binder-antigen. You get a quantitative interaction matrix back in weeks.

The bottleneck isn't design anymore. It's validation.

AI protein design and peptide discovery pipelines now produce candidates faster than any lab can test them with SPR, ITC, ELISA, or one-off pulldowns. Most teams validate the 5 to 20 candidates they have time for, not the ones most likely to work. Real hits get missed. Negative results, which are just as valuable for training your next model, never get generated at all.

Public data

Sparse

Too little interaction coverage

Most public interaction data is binary, inconsistent across sources, and covers only a fraction of the space models need.

Affinity

Rare

Quantitative data at scale

Dense binding-affinity matrices barely exist because traditional methods are too slow and expensive to generate them.

Negatives

Lost

The most informative misses

Teams test their best guesses one at a time. Non-binders and off-targets are filtered out before they can improve the next model.

What we're building

The measurement layer biology never had.

01

Candidate library in

Sequences and targets. The interaction question defined upfront.

02

One pooled experiment

Barcoded, cell-free, all pairs in one tube.

03

Interaction matrix out

Ranked binding, off-targets, structured data for teams and models.

Activate Fellowship · MIT Engine · NVIDIA · Based at MBC Biolabs

Activate FellowshipMIT Engine BlueprintNVIDIAMBC Biolabs

Have a candidate library sitting in a spreadsheet?

Tell us what you're screening and against what. We'll tell you if a pilot makes sense within one call.